The cheapest way to get from Houston to Mcallen, Tx costs only $64, and the quickest way takes just 3¼ hours.. You may opt out of personalised ads at any time. OK. How to get from Houston to Mcallen, Tx by plane, bus or car.. Yes, the driving distance between Houston to Mcallen, Tx is 350 miles. It takes approximately 6h 53m to drive.. Top cities between Houston and McAllen Best stops along Houston to McAllen drive. Map view. Pin.. The direct drive from Houston to McAllen is 349 mi (562 km), and should have a drive time of 6 hrs 30 mins in normal traffic. If you're going on a road trip from Houston to McAllen,.

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The cheapest way to get from Houston, TX to McAllen costs only $65, and the quickest way takes just 3½ hours.. the driving distance between Houston, TX to McAllen is 348 miles. It takes approximately 6h 50m to drive from Houston, TX to McAllen. Get driving directions. Launch map view. Distance: 343.6 mi;. You may opt out of personalised.. and leave at 12:43 pm. drive for about 47 minutes. 1:29 pm Kingsville (Texas) stay for about 1 hour. and leave at 2:29 pm. drive for about 1.5 hours. 4:14 pm arrive in McAllen (Texas) day 2 driving ≈ 3 hours. find more stops.