When the collagen tissue in the front part of your eye weakens, the cornea bulges to form a cone-shaped structure instead of the usual round shape. Such a warped cornea causes keratoconus with blurry vision. Corneal cross-linking surgery prevents progression of the corneal damage by strengthening the fibers in your eye, stabilizing your vision.. The two main approaches to performing corneal collagen cross-linking are "Epi-off" and "Epi-on", with "epi" referring to the corneal epithelium. The standard epi-off surgical approach involves removing 7-9 mm of epithelium with subsequent application of a riboflavin solution at regular interval (2-5 minutes) for 30 minutes, followed by 30.

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Corneal cross linking is a minimally invasive procedure that uses ultraviolet light and eye drops in order to strengthen the collagen fibers in the cornea. The procedure is used for patients with keratoconus, a condition in which the cornea grows thin and weak. During a corneal cross linking procedure, your doctor will first apply riboflavin.. Corneal Collagen Cross-Linking. New York Eye and Ear Infirmary of Mount Sinai (NYEE) is one of a few centers in the New York metropolitan area equipped to perform collagen cross-linking (CXL), a breakthrough technique for treating people with keratoconus and corneal ectasia following refractive surgery. Approved by the FDA in April 2016, CXL.